High Throughput Screening Market Growth Drivers and Forecast by 2028

The high throughput screening market is projected to reach US$ 28,255.71 million by 2028 from US$ 15,997.47 million in 2021. The market is estimated to grow with a CAGR of 8.5% from 2021 to 2028.

High-throughput screening (HTS) is a drug discovery method that enables automated testing of various chemical or biological compounds for a specific biological target. High-throughput screening methods are widely used in the pharmaceutical industry, leveraging robotics and automation to quickly test the biological or biochemical activity of a significant number of molecules, usually drugs. They accelerate target analysis, as large-scale compound libraries can soon be screened cost-effectively. HTS is a valuable tool for assessing pharmacological targets, pharmacologically profiling agonists, and antagonists for receptors (such as GPCRs) and enzymes. Factors such as an increase in investment in research & development by the pharmaceutical and biotechnology industry and the introduction of technologically advanced products in the high throughput screening market are expected to boost the market growth over the years. However, the high cost of high-throughput screening, lack of trained professionals, and complexity in assay development are likely to hamper the market's growth in the coming years.

Market Insights

Increase in Investment in Research and Development by Pharmaceutical and Biotechnology Industry

An increase in R&D expenditures by pharmaceutical and biotechnology companies and significant drug pipelines to treat various chronic diseases such as cardiovascular disorders, cancer, immunological disorders, metabolic disorders, and neurological disorders are notable drivers for the high throughput screening market. Several big and small pharmaceutical companies are involved in developing and manufacturing new molecules for several life-threatening diseases. This has led to the choice of automated high-throughput screening (HTS) methods to screen huge chemical libraries to engageengage the needs of ever-increasing drug target molecules. For instance, an automated high throughput screening system can screen around 10,000 to 100,000 target compounds in a single day. Pharma and biotech companies have substantially invested in high throughput screening techniques in the past decade. For instance, the famous alliance of Millennium Pharmaceuticals, Inc. and Bayer AG has successfully discovered 18 novel drug targets and brought four of them into high throughput screening in just less than eight months. The alliance adopts a novel production approach based on genomics research to get molecules into clinical trials as quickly as possible. High-throughput screening has been regarded as a vital technology in the drug discovery process. For instance, above 60% of Boehringer Ingelheim’s fully developed lead structure optimization programs are due to the successful implementation of HTS. More than 2.5 billion US dollars are annually spent on HTS products and HTS services in the US alone. Large pharmaceutical companies invest up to US$ 35 million annually in screening technologies. A significant proportion of these investments goes into the development of new assays.

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High Throughput Screening Market: Strategic Insights

A rising number of drug targets for screening, which is used for drug discovery and development, and growing investments by government and research institutes will further boost the adoption of HTS techniques. For instance, in December 2020, a UK-based independent integrated drug discovery and pre-clinical contract research organization, Sygnature Discovery has invested around US$ 4.12 million for strengthening its high-throughput screening (HTS) and translational oncology service. Moreover, programs like “Toxicology in the 21st Century”- a joint venture of the US FDA, Environment Protection Agency, and the US National Institute of Health-use automated HTS for testing chemicals, formulation, and environmental drugs, for an extensive toxicological examination and to develop specific pathways associated to the disease to predict the toxicological levels. Such ventures will support the proliferation of the high throughput screening market.

Product and Service-Based Insights

Based on product and service, the high throughput screening market is categorized into consumables, instruments, accessories, software, and services. In 2021, the consumables segment held the largest share of the market and is expected to witness the fastest CAGR during the forecast period.

Report Coverage

Technology-Based Insights

Based on technology, the high throughput screening market is segmented into cell-based assays, lab-on-a-chip, ultra-high-throughput screening, bioinformatics, and label-free technology. In 2021, the cell-based assays segment held the largest share of the market, whereas the lab-on-a-chip segment is expected to grow at the fastest CAGR during the forecast period.

Application-Based Insights

Based on application, the high throughput screening market is segmented into drug discovery, biochemical screening, life sciences research, and other applications. In 2021, the drug discovery segment held the largest share of the market and is expected to grow at the fastest CAGR during the forecast period.

End-User -Based Insights

Based on end-user, the high throughput screening market is segmented into pharmaceutical and biotechnology companies, academic and government institutes, contract research organizations (CRO), and others. In 2021, the pharmaceutical and biotechnology companies segment held the largest share of the market, whereas the contract research organizations (CRO) segment is expected to grow at the fastest CAGR during the forecast period.

Various companies operating in the high throughput screening market are adopting strategies such as product launches, mergers and acquisitions, collaborations, product innovations, and product portfolio expansions to expand their footprint worldwide, maintain brand name, and meet the growing demand from end users.

High Throughput Screening Market Regional Insights

The regional trends and factors influencing the High Throughput Screening Market throughout the forecast period have been thoroughly explained by the analysts at The Insight Partners. This section also discusses High Throughput Screening Market segments and geography across North America, Europe, Asia Pacific, Middle East and Africa, and South and Central America.

High Throughput Screening Market Report Scope

High Throughput Screening Market Players Density: Understanding Its Impact on Business Dynamics

The High Throughput Screening Market is growing rapidly, driven by increasing end-user demand due to factors such as evolving consumer preferences, technological advancements, and greater awareness of the product's benefits. As demand rises, businesses are expanding their offerings, innovating to meet consumer needs, and capitalizing on emerging trends, which further fuels market growth.

High Throughput Screening Market – by Product and Service

• Consumables
  • Reagents and Assay Kits
  • Laboratory Equipment
• Instruments
  • Liquid Handling Systems
  • Detection Systems
• Accessories
• Software
• Services

High Throughput Screening Market – by Technology

• Cell-Based Assays
• Lab-On-A-Chip
• Ultra-High-Throughput Screening
• Bioinformatics
• Label-Free Technology
  • Surface Plasmon Resonance
  • Reflective Interferometry
  • Isothermal Titration Calorimetry
  • Differential Scanning Calorimetry
  • Microcantilevers
  • Carbon Nanotubes
  • Photonic Crystals
  • Others

High Throughput Screening Market – by Application

• Drug Discovery
• Biochemical Screening
• Life Sciences Research
• Other Applications

High Throughput Screening Market – by End User

• Pharmaceutical and Biotechnology Companies
• Academic and Government Institutes
• Contract Research Organizations (CRO)
• Others

High Throughput Screening Market – by Geography

• North America
  • US
  • Canada
  • Mexico
• Europe
  • France
  • Germany
  • Italy
  • UK
  • Spain
  • Rest of Europe
• Asia Pacific (APAC)
  • China
  • India
  • South Korea
  • Japan
  • Australia
  • Rest of Asia Pacific
• Middle East & Africa (MEA)
  • South Africa
  • Saudi Arabia
  • UAE
  • Rest of Middle East & Africa
• South America (SAM)
  • Brazil
  • Argentina
  • Rest of South and Central America

Company Profiles

• Agilent Technologies, Inc.
• Axxam S.P.A.
• Eurofins Scientific
• Corning Incorporated
• Molecular Devices, LLC.
• Hamilton Company
• Merck Group
• Perkinelmer, Inc.
• Tecan Group
• Thermo Fisher Scientific Inc.