Synthetic Biology Market Size & Analysis | Report 2021, 2028

Synthetic Biology Market Forecast to 2028 - COVID-19 Impact and Global Analysis By Products (Enzymes, Chassis Organisms, Oligonucleotides, and Xeno-Nucleic Acids), Technology (Measurement & Modeling, Cloning & Sequencing, Genome Engineering, Gene Synthesis, Nanotechnology, and Others), and Application (Medical Applications, Industrial Applications, Food and Agriculture, Environmental Applications, and Others)

Publication Month : Apr 2022

  • Report Code : TIPHE100000960
  • Category : Biotechnology
  • Status : Published
  • No. of Pages : 217
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The synthetic biology market is expected to grow from US$ 10,544.16 million in 2021 to US$ 37,850.85 million by 2028; it is estimated to grow at a CAGR of 20.0%from 2021 to 2028.

The medical synthetic biology is the science of designing, altering, and building simple organisms to perform specific therapeutic or industrial utilities. The organisms created are genetically modified organisms (GMOs), which do not require a definition that distinguishes them from genetic modifications. The growth of the synthetic biology market is attributed to the increasing investments, technological advancement, and rising numbers of start-up companies. In addition, the emerging trends in synthetic biology are likely to impact the market's growth in the coming years positively.

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Synthetic Biology Market: Strategic Insights

synthetic-biology-market
Market Size Value inUS$ 10,544.16 Million in 2021
Market Size Value byUS$ 37,850.85 Million by 2028
Growth rateCAGR of 20.0% from 2021 to 2028
Forecast Period2021-2028
Base Year2021
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The synthetic biology market is segmented into product, technology, application, and geography. By geography, the market is broadly segmented into North America, Europe, Asia Pacific, the Middle East & Africa, and South & Central America. The synthetic biology market report offers insights and in-depth analysis of the market, emphasizing market trends, technological advancements, market dynamics, and the competitive analysis of the globally leading market players. 

Lucrative Regions for Synthetic Biology Market

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Market Insights
Increasing Investment in Synthetic Biology Drives Synthetic Biology Market

Synthetic biology is an emerging concept that has numerous applications in the chemicals, agriculture, pharmaceuticals, and energy industries. Various start-ups offer gene synthesis products/services for biological processes. For example,  Benchling provides CAD tools, GenScript offers gene synthesis, Ginkgo Bioworks assists in organism engineering, Transcripts (a bioinformatics company) offers solutions facilitating cloud labs/automation, and Glowee offers consumer products. Further, 56 synthetic biology businesses raised more than US$ 3 billion in equity financing in the first half of 2020, compared to 65 companies raising US$ 1.9 billion during the same period in 2020. The new generation of biopharma businesses uses synthetic biology to improve cell treatment and gene therapy and support early cancer detection. Some synthetic biology firms with the most funding in the first half of 2020 are listed below:

Synthetic Biology Firms with Most Funding in First Half of 2020

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Product Insights

Based on product, the global synthetic biology market is segmented into oligonucleotides, chassis organisms, enzymes, and xeno-nucleic acid. The oligonucleotides segment held the largest share of the market in 2021. Moreover, the same segment is anticipated to register the highest CAGR in the market during the forecast period of 2021 to 2028. This is mainly because of the rising application of oligonucleotides in genetic testing/ assays and forensic sciences.

Synthetic Biology Market, by Product (2021–2028)

Synthetic Biology Market, by Product (2021–2028)
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Technology Insights

Based on technology, the global synthetic biology market is segmented into gene synthesis, genome engineering, measurement & modeling, cloning & sequencing, nanotechnology, and others. In 2021, the gene synthesis segment is likely to hold the largest share of the market. However, the genome engineering segment is expected to register the highest CAGR from 2021 to 2028. The growth of the genome engineering segment is owing to the rising applications of genetic engineering and gene therapy.

Application Insights

Based on application, the global synthetic biology market is segmented into medical applications, industrial applications, environmental applications, food and agriculture, and others. The medical applications segment is further segmented into drug discovery & therapeutics and pharmaceuticals. In 2021, the medical applications segment held the largest market share and is expected to register the highest CAGR during 2021–2028.

Product launches and collaborations are highly adopted strategies by the global synthetic biology market players. A few of the recent key market developments are listed below:

  • In February 2022, Thermo Fisher Scientific announced the launch of GeneMapper Software, a flexible genotyping software package that provides DNA sizing and quality allele calls for all Thermo Fisher Scientific electrophoresis-based genotyping.
  • In January 2022, Thermo Fisher Scientific announced the launch of Oncomine BRCA Assay GX. It is a targeted next-generation sequencing (NGS) assay designed to provide comprehensive amplification of all coding regions of the human BRCA1 and BRCA2 genes, enabling accurate and sensitive detection of various mutation classes.
  • In April 2022, Merck KGaA Acquisition of MAST Platform from Lonza, a Leading Automated Bioreactor Sampling System. The acquisition of the MAST platform is another milestone to accelerate innovation in Merck’s Process Solutions business unit.
  • In February 2022, Merck announced the transaction closing to acquire Exalead, following regulatory clearances and the fulfillment of other customary closing conditions, for approximately US$ 780 million in cash.

The COVID-19 pandemic forced many companies in the global synthetic biology market to pause business operations for a short term to follow new government regulations to control the spread of the disease. This halt in operations directly impacted the revenue flow of the global synthetic biology market. In addition, the manufacturing of industrial products ceased, owing to the lack of raw materials and workforce during the lockdown period. Furthermore, no new consignments were received by companies that operate in this sector. Hence, several months' halt in industrial activities and lockdown affected the global synthetic biology industry. The COVID-19 outbreak affected the synthetic biology industry's growth due to the lockdown measures in the countries and the delay in manufacturing and production of raw materials, process materials, and intermediate products used in pharmaceutical and biotechnological companies. The market is anticipated to witness a slow recovery during the forecast period.

Synthetic Biology – Market Segmentation

The global synthetic biology market is segmented based on product, technology application, and geography. Based on product, the market is segmented into oligonucleotides, chassis organisms, enzymes, and xeno-nucleic acid. Based on technology, the synthetic biology market is segmented into gene synthesis, genome engineering, measurement & modeling, cloning & sequencing, nanotechnology, and others. Based on application, the synthetic biology market is segmented into medical applications, industrial applications, enviornmental applications, food and agriculture, and others. By geography, the synthetic biology market is segmented into North America, Europe, Asia Pacific, the Middle East & Africa, and South & Central America.  

Company Profiles

  • THERMO FISHER SCIENTIFIC INC.
  • Agilent Technologies, Inc.
  • MERCK KGaA
  • New England Biolabs
  • Integrated DNA Technologies
  • Twist Bioscience
  • GenScript Biotech Corporation
  • Novozymes A/S
  • Codexis
  • Amyris Inc
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

Products, Technology, and Application

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States

Frequently Asked Questions


Which application segment is fastest growing?

As per application, the medical applications segment is accounted to grow at the fastest CAGR in the market during the forecast period.

Who are the key players in the synthetic biology market?

The synthetic biology market majorly consists of the players such as Thermo Fisher Scientific
Agilent technologies; Merck KGaA; New England Biolabs; Integrated DNA Technologies; Twists Bioscience; Genscript Biotech corporation; Novozymes A/S; Codexis; Amyris among others.

Which product led the synthetic biology market?

The oligonucleotides segment held the largest revenue share in 2021.

What is synthetic biology?

Synthetic biology is a science of designing, altering and building simple organisms to perform specific therapeutic or industrial utilities. The commercialization or industrialization of biology renders processes quicker, cheaper and reliable. The organisms created are known as genetically modified organisms (GMOs), which do not require a definition that distinguishes it from genetic modifications.

The List of Companies - Synthetic Biology Market

  1. Thermo Fisher Scientific
  2. Agilent technologies
  3. Merck KGaA
  4. New England Biolabs
  5. Integrated DNA Technologies
  6. Twists Bioscience
  7. Genscript  Biotech corporation
  8. Novozymes A/S
  9. Codexis
  10. Amyris

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • 3.1 Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • 3.2 Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • 3.3 Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • 3.4 Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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