基于(关键地区、市场参与者、规模和份额)的药物建模软件市场 - 到 2031 年的预测

  • Report Code : TIPRE00013619
  • Category : Healthcare IT
  • Status : Published
  • No. of Pages : 156
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2019年药物建模软件市场价值为62.0522亿美元,预计到2027年将达到112.9985亿美元;预计2020年至2027年复合年增长率为8.1%。

药物建模已成为药物设计过程中的重要工具。基于软件的药物发现和开发方法在新药开发中发挥着关键作用。基于软件的方法,如分子建模、基于结构的药物设计、基于结构的虚拟筛选、配体相互作用和分子动力学被认为是研究药物药代动力学和药效学特性的有力工具。这些方法快速、准确,并为实验结果和作用机制提供了有价值的见解。此外,这些技术的适当实施可能有助于降低药物设计和开发成本。药物开发成本的增加加上药物失败的增加可能会推动预测期内药物建模软件市场的增长。然而,该市场可能会因新兴国家较少采用药物建模软件而受到负面影响。

药物建模软件市场的利润丰厚的区域
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市场洞察

在药物发现中越来越多地采用建模工具

发现和开发具有潜在治疗应用的新药是一项复杂、昂贵且耗时的事业。考虑到这些挑战,已经开发了各种新技术来提高药物发现过程的效率。计算方法已成为多个药物发现项目的重要组成部分。从命中识别到先导化合物优化,许多制药公司广泛使用配体或基于结构的虚拟筛选等技术。在建模的帮助下,可以利用现有数据来深入了解产品的安全性和有效性。由于计算方法的效率,FDA 和 EMA 已纳入模型以支持高效的药物开发。如今,计算机辅助设计(计算机辅助)被用来加速和促进命中识别,优化吸收、分布、代谢和毒性特征,以避免安全问题。常用的计算机方法包括基于配体的药物设计、基于结构的药物设计和定量结构活性。

这些方法速度更快,并为实验结果和作用机制提供了有价值的见解。此外,各种制药公司已经开始采用这些技术以获得更好的结果。例如,2020年4月,勃林格殷格翰与Insilico Medicine合作,利用人工智能(AI)技术来识别潜在的治疗靶点。这些方法对于病毒爆发和紧急药物研发非常有用。例如,2020 年 8 月,Certara 宣布开发新的 COVID-19 疫苗生物模拟平台。该公司已与制药公司合作,加速药物发现和开发。其 QSP 平台在改善生物制药研发和为决策提供信息方面具有巨大潜力。通过创建虚拟患者和虚拟试验,这个新的疫苗平台将促进一系列感染 COVID-19 的患者的剂量策略。此外,许多研究组织也开始采用药物建模技术来加快研究进程。例如,西南研究所 (SwRI) 正在扩大虚拟筛选药物化合物的能力,以用于治疗 COVID-19 和其他传染病。最近,SwRI 提高了 Rhodium 软件的容量,每天可扫描 250,000 种药物化合物。因此,上述因素预计将在预测期内推动药物建模软件市场的增长。

基于产品类型的见解

根据产品类型,药物建模软件市场分为数据库、软件等。软件领域在2019年占据了最大的市场份额。成功的药物发现、开发以及将单一新药推向市场,成本约为10亿美元,需要近12年的时间才能完成。成本高、持续时间不足且时间长、风险高、结果不确定、程序高度复杂是开发新药的主要挑战。为了克服这些问题,迫切需要采用新的且具有成本效益的药物发现和设计方法,例如软件和计算机辅助药物设计和分子对接。例如,薛定谔提供的平台花费了数十年的时间来改进计算算法,以准确计算分子的基本属性。该公司使用 NVIDIA GPU 生成和评估 PB 级数据,以加速药物发现,这是对缓慢而昂贵的实验室工作的传统流程的改进。

探索软件基于模型的工具已成为制药行业药物发现和开发的重要方式,在将新的生物活性药物扩展到一系列治疗领域方面发挥着至关重要的作用。正确使用软件和基于计算机的现代方法减少了药物发现中的一些障碍并加速了新药开发。

全球药物建模软件市场,按产品类型划分– 2019年& 2027

基于应用的见解

基于应用,药物建模软件市场分为药物发现和开发、医学成像、计算生理医学、药物靶标预测分析、疾病建模、模拟软件、细胞模拟等。药物发现过程很复杂,包括设计实用且商业上可行的药物的跨学科努力。在制药、医学和其他科学研究中,计算机在开发新化合物以寻求更好的治疗剂方面发挥着重要作用。

此外,计算能力以及X射线晶体学和NMR等先进分析技术提高了CADD(计算机辅助药物设计)在该领域的应用制药行业的许多批准药物的发现在很大程度上归功于 CADD 工具,例如用于治疗高血压的血管紧张素转换酶 (ACE) 抑制剂卡托普利、用于治疗黄斑囊样水肿的碳酸酐酶抑制剂多佐胺、肾素抑制剂阿利吉仑,用于治疗原发性高血压;人类免疫缺陷病毒(HIV)蛋白酶抑制剂沙奎那韦、利托那韦和茚地那韦用于治疗艾滋病毒。此外,CADD 和生物信息学工具还具有节省成本、缩短上市时间、深入了解药物受体相互作用以及加快药物发现和开发等优势。药物建模软件为药物发现和药物开发提供的这些优势将推动预测期内的细分市场增长。

此外,新平台的开发将进一步提供利润丰厚的利润。机会。例如,2020 年 3 月 16 日,富士通与 Polarisqb 合作试点了一个突破性的新药物发现平台,旨在支持制药公司快速、经济高效地将重要药物推向市场。该平台利用量子启发技术、机器学习、混合量子力学和分子力学模拟 (QM/MM) 来改变药物发现的过程。 2019 年 7 月 19 日,马里兰大学药学院教员成立的新公司 Pumas-AI 宣布推出首个面向药物研究人员和临床医生的尖端软件平台,称为药物建模与模拟 (Puma) 。它是一个基于 Julia 编程语言的综合平台,包含多个模块,旨在满足制药行业分析师的需求,同时还致力于推进临床环境中的治疗创新。 2019 年 8 月,总部位于英国伦敦的 Evaluate(一家为研究人员和药物开发商提供软件服务的公司)发布了 Product Specific PTRS(技术和监管成功概率),这是一个处理数据以预测药物成功可能性的平台。然而,药物靶点的预测分析预计在预测期内将出现显着的增长。

战略洞察

公司通常采用产品发布和扩张战略来扩大其全球足迹,满足不断增长的需求,并提高其在全球的影响力。

药物建模软件市场的主要参与者采用产品创新策略来满足全球不断变化的客户需求,这也使参与者能够在全球范围内维护其品牌名称。

按产品类型

  •  数据库
  • 软件
  • 其他

按应用划分

  • 药物发现和开发
  • 计算生理医学
  • 疾病模型
  • 医学影像
  • 药物靶点预测分析
  • 模拟软件
  • 细胞模拟
  • 其他

按地理位置

  • 北美
    • 美国
    • 加拿大
    • 墨西哥
  • 欧洲
    • 法国
    • 德国
    • 意大利
    • 英国
    • 西班牙
  • 亚太地区 (APAC)
    • 中国
    • 印度
    • li>
    • 韩国
    • 日本
    • 澳大利亚
  • 中东和非洲非洲 (MEA)
    • 南非
    • 沙特阿拉伯
    • 阿联酋
  • 南美洲和中美洲 (SCAM )
    • 巴西
    • 阿根廷

公司简介

  • Crown Bioscience Inc.
  • 化学计算集团 Ulc
  • Nimbus Therapeutics
  • Schrödinger, Inc.
  • 达索系统
  • Genedata Ag
  • Biognos Ab
  • Compugen Ltd
  • Acellera ltd.
  • Leadscope,公司
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

This text is related
to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

This text is related
to country scope.

The List of Companies - Drug Modeling Software Market

  1. Crown Bioscience Inc.
  2. Chemical Computing Group Ulc
  3. Nimbus Therapeutics
  4. Schrödinger, Inc.
  5. Dassault Systèmes
  6. Genedata Ag
  7. Biognos Ab
  8. Compugen Ltd
  9. Acellera ltd.
  10. Leadscope, Inc

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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