The protein expression market is expected to reach US$ 4,000.67 million in 2028 from US$ 2,221.73 million in 2021. The market is estimated to grow with a CAGR of 8.8% from 2021-2028.
The scope of the Protein Expression market includes product type, services, application, end user, and region. Based on region, the Protein Expression market is segmented into North America, Europe, Asia Pacific, Middle East & Africa, and South and Central America. The report offers insights and in-depth analysis of the Protein Expression market emphasizing on various parameters such as market trends, technological advancements, market dynamics, and competitive landscape analysis of leading market players across the world. It also includes COVID–19 impact analysis across the regions.
Lucrative Regions for Protein Expression Market
- Sample PDF showcases the content structure and the nature of the information with qualitative and quantitative analysis.
- Sample PDF showcases the content structure and the nature of the information with qualitative and quantitative analysis.
Market Insights
Increasing Applications of Protein Expression
Protein expression, an integral tool in biological research, is increasingly vital as a pharmaceutical production mechanism for biological therapeutics. The combination of old technologies, such as artificial enzymes, and new next-generation expression systems is revitalizing protein expression protocols. The development of genetic engineering and cloning has opened many possibilities for the expression and isolation of heterologous proteins for research purposes. Considerable advances in technology have enabled the expression and isolation of recombinant proteins on a large scale.
The demand for recombinant proteins for human application is increasing day by day. There is a huge demand for novel and improved bioprocessing strategies that are cost-effective and time-saving. The continuous improvement in biopharmaceutical expression systems has led to the production of quality products. Modern molecular biology techniques are at the forefront of the production of biopharmaceutical proteins using various prokaryote or eukaryote expression systems. Different innovative techniques, such as systems biology, metabolic engineering, and CRISPR/Cas systems, can be applied for strain engineering to improve bioprocess performance and generate biologically active and stable proteins.
The global burden of dengue is rapidly increasing and will continue until the development of an effective vaccine against it. Various vaccine candidates for dengue are at preclinical and clinical trials stages of development based on different approaches. A few vaccines are a tetravalent, live attenuated virus, purified inactivated virus, recombinant proteins subunit, plasmid DNA, and virus-vectored dengue vaccines. Recent progress on recombinant subunit-based dengue vaccine candidates using various approaches, such as fusion with other immunogenic epitopes, use of a novel adjuvant, protein expression in different host systems, designer vaccine, and VLPs development, is opening new avenues for the development of a fully efficacious vaccine against dengue.
Currently, more than 65 million confirmed cases and over 1.5 million deaths are reported. The COVID-19 pandemic has led to significant health, social, and global economic crises. The development of a vaccine for COVID-19 is an effective strategy to control the outbreak. It is required that the vaccine is produced at high speed and is easily scalable. Recombinant protein, viral-vectored or nucleic acid-based (recombinant plasmid DNA and mRNA) vaccines need to be considered to shorten the vaccine production timeframe. The use of protein expression is increasing during vaccine development due to the advantages of recombinant protein, which drives the growth of the protein expression market.
Product Type-Based Insights
Based on product type, the protein expression market is segmented into instruments, reagents, expression vectors, and competent cells. The reagents segment held the largest share of the market in 2021. Also, the reagents segment is estimated to register the highest CAGR of 9.5% in the market during the forecast period.
Global Protein Expression Market, by Product Type – 2021 & 2028
- Sample PDF showcases the content structure and the nature of the information with qualitative and quantitative analysis.
- Sample PDF showcases the content structure and the nature of the information with qualitative and quantitative analysis.
Services-Based Insights
Based on services, the protein expression market is segmented into antibody development & production, protein expression & production, hybridoma one-stop services, stable cell line development, bioanalytical assay services. The antibody development & production segment held the largest share of the market in 2021. However, same segment is estimated to register the highest CAGR of 9.7% in the market during the forecast period.
Application-Based Insights
Based on application, the protein expression market is segmented into research, therapeutic, industrial. The therapeutic segment held the largest share of the market in 2021 and same segment is estimated to register the highest CAGR of 9.4% in the market during the forecast period.End User-Based Insights
Based on end user, the protein expression market is segmented into pharmaceutical and biotechnology companies, academic research institutes, and contract research organizations. The pharmaceutical and biotechnology companies segment held the largest share of the market in 2021. Also, the segment is estimated to register the highest CAGR of 5.6% in the market during the forecast period.
Customize Research To Suit Your Requirement
We can optimize and tailor the analysis and scope which is unmet through our standard offerings. This flexibility will help you gain the exact information needed for your business planning and decision making.
Protein Expression Market: Strategic Insights
Market Size Value in US$ 2,221.73 Million in 2021 Market Size Value by US$ 4,000.67 Million by 2028 Growth rate CAGR of 8.8% from 2021-2028 Forecast Period 2021-2028 Base Year 2021
Akshay
Have a question?
Akshay will walk you through a 15-minute call to present the report’s content and answer all queries if you have any.
Speak to Analyst
Customize Research To Suit Your Requirement
We can optimize and tailor the analysis and scope which is unmet through our standard offerings. This flexibility will help you gain the exact information needed for your business planning and decision making.
Protein Expression Market: Strategic Insights
| Market Size Value in | US$ 2,221.73 Million in 2021 |
| Market Size Value by | US$ 4,000.67 Million by 2028 |
| Growth rate | CAGR of 8.8% from 2021-2028 |
| Forecast Period | 2021-2028 |
| Base Year | 2021 |
Akshay
Have a question?
Akshay will walk you through a 15-minute call to present the report’s content and answer all queries if you have any.
Speak to Analyst
Inorganic strategies such as partnerships, and mergers and acquisitions are commonly adopted by companies to cater to changing customer demand and maintain their brand name across the world. Market players operating in the Protein Expression market also adopt organic strategies such as product launch and expansion to outstretch their footprint and product portfolio worldwide as well as to meet the growing demand.
By Product Type
- Competent Cells
- Expression Vectors
- Reagents
- Instruments
By Services
- Antibody Development & Production
- Protein Expression & Production
- Hybridoma One-Stop Services
- Stable Cell Line Development
- Bioanalytical Assay Services
By Application
- Research
- Therapeutic
- Industrial
By End User
- Pharmaceutical and Biotechnology Companies
- Contract Research Organizations
- Academic Research Institutes
- Others
By Geography
- North America
- US
- Canada
- Mexico
- Europe
- France
- Germany
- Italy
- UK
- Spain
- Rest of Europe
- Asia Pacific (APAC)
- China
- India
- South Korea
- Japan
- Australia
- Rest of APAC
- Middle East & Africa (MEA)
- South Africa
- Saudi Arabia
- UAE
- Rest of MEA
- South and Central America (SCAM)
- Brazil
- Argentina
- Rest of SCAM
Company Profiles
- Thermo Fisher Scientific, Inc.
- GenScript
- Merck KGaA
- Agilent Technologies, Inc.
- Takara Bio Inc.
- Bio-Rad Laboratories, Inc.
- QIAGEN
- New England Biolabs.
- Promega Corporation
- Oxford Expression Technologies Ltd
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
Protein Expression Market Forecast to 2028 - Covid-19 Impact and Global Analysis - By Product ; Services ; Application ; End User and Geography
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States
Frequently Asked Questions
Protein expression is a process in which proteins are synthesized, modified and regulated. Protein expression involves laboratory techniques & procedures which aid in manufacture of proteins. The technique allows to produce and purify the desired protein, either inside or outside a cell. The proteins synthesized using protein expression technique can be used for industrial processes or to diagnose and to treat diseases. Protein expression provides substrates or enzymes required for further analysis
Driving factors such as an development in the arena of proteomics and biotechnology industry, rising incidences of chronic and autoimmune diseases, rise in the awareness among people regarding protein expression, increasing focus on research and development process, growing usage of protein expression technologies in industrial protein manufacturing organizations, and rise in adoption of protein-based drugs over non-protein-based drugs are the prime growth drivers of protein expression market. In addition, increase in adoption of protein expression in emerging economies such as China, India and others, will create new opportunities for protein expression market. However, higher cost of the research and development, and complex government approval processes are the key restraints for protein expression market.
The Protein Expression market is anticipated to grow around 8.8% CAGR amid the forecast period 2021-2028.
North America held highest market share in 2021.
Asia Pacific is projected to be the fastest growing region in the global market.
The costs of the Protein Expression are much higher, and they may cost US$ 300–1500, or more, per type. The cost may also differ from product to product types.
The List of Companies - Protein Expression Market
- Thermo Fisher Scientific, Inc.
- GenScript
- Merck KGaA
- Agilent Technologies, Inc.
- Takara Bio Inc.
- Bio-Rad Laboratories, Inc.
- QIAGEN
- New England Biolabs.
- Promega Corporation
- Oxford Expression Technologies Ltd
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- 3.1 Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- 3.2 Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
Trends and growth analysis reports related to Protein Expression Market
Aug 2021
Bioprocessing Market
Size and Forecast (2021 - 2031), Global and Regional Share, Trend, and Growth Opportunity Analysis Report Coverage: By Product (Instruments, and Consumables and Accessories), Scale of Operation (Commercial Operations and Clinical Operations), Process (Downstream Bioprocess and Upstream Bioprocess), Application (Monoclonal Antibodies, Vaccines, Recombinant Protein, Cell and Gene Therapy, and Others), End User (Biopharmaceutical Companies, Contract Manufacturing Organization, and Others), and Geography (North America, Europe, Asia Pacific, South & Central America, and Middle East & Africa)
Aug 2021
Bioproduction Market
Size and Forecasts (2020 - 2030), Global and Regional Share, Trends, and Growth Opportunity Analysis Report Coverage: By Product (Biologics and Biosimilars, Vaccines, Cell and Gene Therapies, Nucleic Acid Therapeutics, and Others), Application (Rheumatoid Arthritis, Hematological Disorders, Cancer, Diabetes, Cardiovascular Diseases, and Others), Equipment (Upstream Equipment, Downstream Equipment, Bioreactors, and Consumables and Accessories), End User (Biopharmaceutical Companies, Contract Manufacturing Organizations, and Others), and Geography (North America, Europe, Asia Pacific, Middle East & Africa, and South & Central America)
Aug 2021
ELISA Diagnostic Test Market
Size and Forecasts (2020 - 2030), Global and Regional Share, Trends, and Growth Opportunity Analysis Report Coverage: By Adoption (Human and Veterinary), Test Type (Sandwich ELISA, Indirect ELISA, Competitive ELISA, and Multiple & Portable ELISA), Application (Autoimmune Diseases, Infectious Diseases, Cancer Diagnosis, Protein Quantification, and Others), End User (Hospitals & Diagnostic Centers, Pharmaceutical & Biotechnology Companies, Veterinary Hospitals & Diagnostic Laboratories, and Others), and Geography (North America, Europe, Asia Pacific, South & Central America, and Middle East & Africa)
Aug 2021
Swine Diagnostics Market
Size and Forecasts (2022 - 2030), Global and Regional Share, Trends, and Growth Opportunity Analysis Report Coverage: By Product Type [Immunoassays Kits, PCR Kits, Hemagglutination Inhibition (HI), and Others], Sample Type (Blood, Oral Fluids, Nasal Swabs, Tissue Samples, and Others), Disease [African Swine Fever (ASF)/Classical Swine Fever (CSF), Respiratory Diseases, Porcine Circovirus, Porcine Epidemic Diarrhea, Swine Dysentery, and Others], End User (Veterinary Hospitals, Veterinary Clinics, and Other End Users), and Geography
Aug 2021
Microbial Identification Methods Market
Size and Forecasts (2020 - 2030), Global and Regional Share, Trends, and Growth Opportunity Analysis Report Coverage: By Method (Genotypic, Phenotypic, and Proteotypic), Type (Bacterial Identification System, Microbial Enumeration System, Bacterial Resistance Identification Systems, Microbiology Analyzer, and Others), and Geography (North America, Europe, Asia Pacific, Middle East & Africa, and Latin America)
Aug 2021
Biopharmaceuticals Market
Forecast to 2028 - COVID-19 Impact and Global Analysis By Product Type (Monoclonal Antibodies, Recombinant Vaccines, Conventional Vaccines, Recombinant Growth Factors, Purified Proteins, Recombinant Proteins, Recombinant Hormones, Recombinant Enzymes, Cell & Gene Therapies, Cytokines/Interferon/Interleukins, and Others) and Application (Oncology, Inflammatory & Infectious Disease, Autoimmune Disorders, Metabolic Disorders, Hormonal Disorders & Growth Failure, Cardiovascular Diseases, Neurological Diseases, and Others)
Aug 2021
GMP Cell Therapy Consumables Market
Forecast to 2028 - COVID-19 Impact and Global Analysis by Product (Kits, Reagents/Molecular Biology Reagents, Growth Factors/Cytokines and Interleukins, and Others), Cell Therapy (NK Cell Therapy, Stem Cell Therapy, T-Cell Therapy, and Others), Process (Cell Collection and Characterization/Sorting and Separation, Cell Culture and Expansion/Preparation, Cryopreservation, Cell Processing and Formulation, Cell Isolation and Activation, Cell Distribution/Handling, Process Monitoring and Control/Readministration/Quality Assurance, and Others), and End Use (Clinical, Commercial, and Research)
Aug 2021