基因治疗市场基于(关键地区、市场参与者、规模和份额)- 到 2030 年的预测

  • Report Code : TIPHE100001165
  • Category : Biotechnology
  • Status : Data Released
  • No. of Pages : 150
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【研究报告】基因治疗市场预计将从2023年的51.1亿美元增至2031年的256.9亿美元;预计 2023-2031 年市场复合年增长率为 14.3%。

市场洞察和分析师观点:

基因治疗是一种通过灭活致病物质来治疗疾病的过程基因,用该基因的健康副本替换致病基因,或者将新的或修改的基因引入体内以帮助治疗和预防疾病。基因治疗可分为体内基因治疗和离体基因治疗。基因疗法的目的是用正常基因替换或纠正有缺陷的基因,使身体产生正常功能所需的正确蛋白质或酶,从而有可能治愈疾病的根本原因。全球范围内遗传疾病和癌症的患病率不断上升,以及 FDA 批准基因疗法的数量不断增加,有利于基因疗法市场的增长。此外,基因治疗市场趋势包括基因治疗技术的进步,这将有利于未来市场的增长。

增长动力:

生物技术的进步带动了发展针对多种适应症的治疗方法。基因疗法被用于治疗各种疾病,例如癌症、神经系统疾病和遗传性疾病。由于美国食品和药物管理局 (FDA) 批准的产品的可用性,基因疗法在全球范围内得到广泛采用。以下是 FDA 近年来批准的基因治疗产品的一些示例:

2023 年 12 月,FDA 批准了两种基于细胞的镰状细胞病基因疗法。 Bluebird Bio 的 Lyfgenia (lovotibeglogene autotemcel) 已被批准用于 12 岁及以上有血管闭塞事件史的镰状细胞病患者。它与 Vertex Pharmaceuticals 和 CRISPR Therapeutics 的 Casgevy (exagamglogene autotemcel) 一起获得批准。 2023 年 6 月,FDA 批准了 Roctavian,一种基于腺相关病毒载体的基因疗法,用于治疗患有严重 A 型血友病的成人,且无需预先存在抗体腺相关病毒血清型 5。遗传性 A 型血友病是一种严重的出血性疾病,由基因突变引起,该基因突变负责产生因子 VIII (FVIII),这是一种能够促进血液凝固的蛋白质。 Roctavian 是一种一次性基因治疗产品,含有携带凝血因子 VIII 基因的病毒载体。2023 年 6 月,FDA 批准了 Elevidys,这是第一个治疗 4 至 5 岁儿童杜氏肌营养不良症的基因疗法。已确认杜氏肌营养不良症基因突变,并且没有妨碍该疗法治疗的既往病史。2022 年 11 月,FDA 批准了由 CSL Behring LLC 生产的 HEMGENIX,一种重组腺相关病毒 5 型基因治疗患有某些类型的 B 型血友病的成年患者。因此,这些基因疗法的越来越多的批准正在推动基因疗法市场的增长。

战略见解

报告细分和范围:

基因治疗市场分析是通过考虑以下部分进行的:载体、适应症、递送模式和地理位置。根据载体,市场分为非病毒载体和病毒载体。从适应症来看,市场分为神经系统疾病、癌症、杜氏肌营养不良症、肝病等适应症。就递送模式而言,市场分为体内和体外。基因治疗市场报告的范围涵盖北美(美国、加拿大和墨西哥)、欧洲(法国、德国、英国、西班牙、意大利和欧洲其他地区)、亚太地区(中国、日本、印度、澳大利亚、韩国以及亚太其他地区)、中东和非洲(沙特阿拉伯、南非、阿联酋以及中东和非洲其他地区)以及南美洲和中美洲(巴西、阿根廷和南美洲和中美洲其他地区)。

细分分析:

基因治疗市场按载体分为非病毒载体和病毒载体。病毒载体细分市场在 2023 年占据了重要的市场份额。预计 2023 年至 2030 年市场复合年增长率将更高。

基因治疗市场,按 Vector - 2023 年和 2031 年

根据适应症,市场分为神经系统疾病、癌症、杜氏肌营养不良症、肝病和其他适应症。癌症细分市场在 2023 年占有重要的基因治疗市场份额,预计 2023-2030 年复合年增长率最高。

根据递送模式,市场分为体内和体外。体内细分市场在 2023 年占据了重要的基因治疗市场份额,预计 2023 年至 2030 年期间复合年增长率将更高。体内基因治疗可以实现系统治疗,这意味着它可以到达全身的多个部位和器官。这对于影响多个区域或具有系统症状的疾病特别有帮助,从而可以采取全面的治疗方法。此外,病毒载体、纳米粒子和脂质载体等先进递送技术的发展提高了体内治疗的有效性和特异性。这些进步促进了遗传物质的靶向递送,并提高了治疗的安全性和有效性。

区域分析:

从地理上看,基因治疗市场分为北美、欧洲、亚太地区、南美和南亚地区。和中美洲、中东和非洲。 2023 年,北美占据了重要的市场份额。 2023年,美国主导了该地区的基因治疗市场。北美市场的增长归因于遗传性疾病患病率的不断上升、癌症患者数量的增加、政府资助的增加、先进基因疗法在疾病治疗中的采用不断增加以及产品批准的不断增加。

根据美国疾病控制与预防中心 (CDC) 表示,2020 年美国新诊断出约 1,603,844 例癌症病例,其中 602,347 例癌症死亡。每 10 万人中报告了 403 例新癌症病例。此外,根据国际癌症研究机构的数据,预计到 2040 年,新增癌症病例将达到 3020 万。根据美国政府问责办公室 2021 年 10 月发布的估计,约有 25 至 3000 万人患有罕见癌症。国内的疾病;近50%的罕见病患者是儿童。罕见疾病通常是基因突变的结果;据估计,80% 的罕见病是遗传性的。

根据美国国立卫生研究院 2021 年 10 月的更新,10 家制药公司和 5 家非营利组织已合作加速基因疗法的开发3000万美国人患有罕见疾病。美国 FDA 已批准 7 种细胞和基因治疗药物,新产品线达到约 1,200 种实验疗法。其中一半处于 2 期临床试验中,根据《化学与工程新闻》2023 年报告的估计,细胞疗法的年销售额增长预计为 15%,基因疗法的年销售额增长约为 30%。上述所有这些因素都促进了该地区基因治疗市场规模的不断增长。

行业发展和未来机遇:

在全球基因治疗市场运营的市场参与者采取的一些举措是如下:

“2022 年 1 月,Ori Biotech Ltd 在超额认购的 B 轮融资中获得了超过 1 亿美元的资金,以在市场上推出创新的细胞和基因治疗制造平台。” 2020 年 1 月,Astellas Pharma Inc. 收购了 Audentes Therapeutics, Inc.。此次收购使合并后的公司成为基于 AAV 的基因医学领域的全球领导者。竞争格局和主要公司:

基因治疗市场预测可以提供帮助利益相关者规划他们的增长战略。诺华公司、安斯泰来制药公司、百时美施贵宝公司、蓝鸟生物公司、CSL Behring、赛诺菲、罗氏公司、第一三共、百健和牛津生物医学公司都是基因治疗领域的知名参与者市场报告。这些公司专注于推出新的高科技产品、现有产品的进步以及地域扩张,以满足全球不断增长的消费者需求。
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

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Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

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Frequently Asked Questions


What are the driving and restraining factors for the gene therapy market?

The factors driving the growth of the gene therapy market include the increasing burden of genetic diseases and the rising number of FDA approvals of gene therapies. However, the high cost of gene therapy products hampers the growth of the gene therapy market.

What is gene therapy?

Gene therapy is a process for the treatment of diseases by inactivating a disease-causing gene, replacing a disease-causing gene with a healthy copy of the gene, or introducing a new or modified gene into the body to help treat and prevent the disease.

What are the growth estimates for the gene therapy market till 2031?

The gene therapy market is expected to be valued at US$ 25.69 billion in 2031.

Which segment is dominating the gene therapy market?

The global gene therapy market is segmented based on vectors, indication, and delivery mode. Based on indication, the gene therapy market is categorized into neurological diseases, cancer, Duchenne muscular dystrophy, hepatological diseases, and other indications. The cancer segment held a significant market share in 2023 and is anticipated to record the highest CAGR in the market during 2023–2031.

What was the gene therapy market size in 2023?

The gene therapy market was valued at US$ 5.11 billion in 2023.

Who are the major players in the gene therapy market?

The gene therapy market majorly consists of the players, including Novartis AG, Astellas Pharma Inc., Bristol-Myers Squibb Company, Bluebird Bio Inc., CSL Behring, Sanofi, F. Hoffmann-La Roche Ltd, Daiichi Sankyo, Biogen, and Oxford Biomedica.

The List of Companies - Gene Therapy Market

  1. Novartis AG
  2. Astellas Pharma Inc.
  3. Bristol-Myers Squibb Company
  4. Bluebird Bio Inc.
  5. Sanofi
  6. F. Hoffmann-La Roche Ltd
  7. Daiichi Sankyo
  8. CSL Behring
  9. Biogen
  10. Oxford Biomedica.

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