Closed System Transfer Device Market Size, Growth by 2028

Closed Systems Drug Transfer Devices Market Forecast to 2027 - COVID-19 Impact and Global Analysis by Closing Mechanism (Push-to-turn Systems, Color-to-color Alignment Systems, Luer-lock Systems, Click-to-lock Systems); Type (Membrane-to-membrane Systems, Needleless Systems); Technology (Diaphragm-based Devices, Compartmentalized Devices, Air Cleaning/Filtration Devices); Component (Vial Access Devices, Syringe Safety Devices, Bag/Line Access Devices, Accessories); End User (Hospitals and Clinics, Oncology Centers, Others), and Geography

Publication Month : Sep 2020

  • Report Code : TIPRE00004560
  • Category : Medical Device
  • Status : Published
  • No. of Pages : 218
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The closed system drug transfer devices market was valued at US$ 374.48 million in 2019 and is projected to reach US$ 1,661.83 million by 2027; it is expected to grow at a CAGR of 20.5% from 2020 to 2027.


The closed system drug transfer device provides protection against hazardous drugs or vapors during drug preparation and administration. It comprises components which enable filtering of dangerous vapors out of the system. Closed system drug transfer devices play a major role in protection of healthcare professionals from antineoplastic as well as other harmful medications. Growing emphasis on implementation of occupational health and safety standards by government authorities are offering lucrative opportunity for the growth of the market. The closed system drug transfer devices market growth is mainly attributed to increase in adoption of chemotherapy and improvement of regulatory guidelines regarding hazardous drugs. Moreover, rising number of chemotherapeutic drug approvals is further expected to foster the market growth during the forecast period. However, the lack of regulatory guidelines regarding health workers’ safety in emerging countries limits the growth of the market.

The closed system drug transfer device market in Europe is highly affected due to coronavirus. For instance, the necessity to divert healthcare staff and resources to address the COVID-19 pandemic has resulted in the suspension of cancer screening programs for asymptomatic patients in many countries. In March 2020, the Welsh government and the Scottish government suspended screening programs for breast, cervical, and bowel cancer.

Lucrative Regions for Closed System Drug Transfer Devices Market

Lucrative Regions for Closed System Drug Transfer Devices Market

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Market Insights

Growing Adoption of Chemotherapy

Several hazardous drugs such as antineoplastics, monoclonal antibodies, and antibiotics are used during patient treatments protocols. Pharmacists, physicians, nurses, and other healthcare workers are at great risk of exposure to such hazardous drugs. The cancer treatment comprises utilization of antineoplastic drugs that can cause several health implications, if ingested. The antineoplastic can have severe impact during pregnancies, and the exposure can lead to chromosomal abnormalities. The surface contamination of chemotherapy treatment can impact not only healthcare professionals but also patients and their families. Increasing number of cancer cases are anticipated to boost the adoption of chemotherapy across the globe. For instance, according to the World Health Organization, in 2018, ~9.6 million deaths were reported due to cancer across the world. According to the study conducted by American Cancer Society in 2019–2020, chemotherapy is the most common cancer treatment among stage III breast cancer women as ~56.0% of stage III breast cancer cases prefer chemotherapy in the US. Further, according to the same study, ~43.0% of the patients preferred chemotherapy for the treatment of large B-cells during 2012–2016. Thus, the consequent surge in the adoption of chemotherapies would eventually drive the demand for closed system drug transfer devices in the coming years.

Closing Mechanism-Based Insights

Based on closing mechanism, the closed system drug transfer devices market is segmented into push-to-turn systems, color-to-color alignment systems, luer-lock systems, and click-to-lock systems. The push-to-turn systems segment held the largest share of the market in 2019. However, the luer-lock systems segment is anticipated to register the highest CAGR in the market during the forecast period. Push-to-turn is one of the closing mechanisms that successfully prevents aerosol and vapor leakage from the vial. Increasing spending on occupational health of healthcare professionals and growing preference for chemotherapies are likely to drive the demand for closed system drug transfer devices, which would eventually drive the segment growth.

Closed System Drug Transfer Devices Market, by Closing Mechanism – 2019 and 2027

Closed System Drug Transfer Devices Market, by Closing Mechanism – 2019 and 2027

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Type-Based Insights

In terms of type, the closed system drug transfer devices market is segmented into membrane-to-membrane systems and needleless systems. The membrane-to-membrane systems segment held the largest share of the market in 2019. However, the needleless systems segment is anticipated to register the highest CAGR in the market during the forecast period. The membrane-to-membrane system prohibits transfer of environmental contaminants into the system and leakage of hazardous gases outside the system. Moreover, the membrane-to-membrane system prevents introduction of harmful vapor aerosols and spills outside the system with the help of air-cleansing technology.

Technology-Based Insights

Based on technology, the closed system drug transfer devices market is segmented into diaphragm-based devices, compartmentalized devices, and air cleaning/filtration devices. The diaphragm-based devices systems segment held the largest share of the market in 2019. However, the compartmentalized devices segment is anticipated to register the highest CAGR in the market during the forecast period. Diaphragm-based devices are particularly used during pressure equalization. The technology prohibits the diffusion of hazardous vapors and offers protection from harmful exposure.

Component-Based Insights

In terms of component, the closed system drug transfer devices market is segmented into vial access devices, syringe safety devices, bag/line access devices, and accessories. The vial access devices segment held the largest share of the market in 2019. However, the syringe safety devices segment is anticipated to register the highest CAGR in the market during the forecast period. Vented vial access devices are used to safely access drugs for needleless drug preparation and administration. The vial access devices are projected to register considerable growth due to increasing drug administration. Moreover, vial access devices are required to be connected with the closed system drug transfer devices for drug administration.

End User-Based Insights

Based on end user, the closed system drug transfer devices market is segmented into hospitals & clinics, oncology centers, and others. The hospitals & clinics segment held the largest share of the market in 2019. The segment is anticipated to register the highest CAGR in the market during the forecast period. The hospitals segment is estimated to hold considerable share as majority of the patients in emerging countries as well as developed countries prefer to visit hospitals for any kind of health-related problems. Further, increasing number of hospitals and growing accessibility in emerging countries are estimated to offer lucrative growth opportunity for the hospital and clinics segment during the forecast period.

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Closed Systems Drug Transfer Devices Market: Strategic Insights

closed-system-transfer-devices-market
Market Size Value inUS$ 374.48 Million in 2019
Market Size Value byUS$ 1,661.83 Million by 2027
Growth rateCAGR of 20.5% from 2020-2027
Forecast Period2020-2027
Base Year2020
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Product launches, mergers and acquisitions, collaborations, and expansions are the commonly adopted strategies by various companies to expand their footprint worldwide and meet the growing demand by expanding their respective product portfolios. The players operating in the closed system drug transfer devices market have adopted product innovations strategy to cater to changing customer demand worldwide, which also permits them to maintain their brand name globally.

Closed System Drug Transfer Devices Market – by Closing Mechanism

  • Push-to-Turn Systems
  • Luer-Lock Systems
  • Color-to-Color Alignment Systems
  • Click-to-Lock Systems

Closed System Drug Transfer Devices Market – by Type

  • Membrane-to-Membrane Systems
  • Needleless Systems

Closed System Drug Transfer Devices Market – by Technology

  • Diaphragm-Based Devices
  • Compartmentalized Devices
  • Air Cleaning/Filtration Devices

Closed System Drug Transfer Devices Market – by Component

  • Vial Access Devices
  • Syringe Safety Devices
  • Bag/Line Access Devices
  • Accessories

Closed System Drug Transfer Devices Market – by End User

  • Hospitals and Clinics
  • Oncology Centers
  • Others

Closed System Drug Transfer Devices Market – by Geography

  • North America
    • US
    • Canada
    • Mexico
  • Europe
    • France
    • Germany
    • Italy
    • UK
    • Spain
    • Rest of Europe
  • Asia Pacific (APAC)
    • China
    • India
    • South Korea
    • Japan
    • Australia
    • Rest of APAC
  • Middle East & Africa (MEA)
    • South Africa
    • Saudi Arabia
    • UAE
    • Rest of MEA
  • South and Central America (SCAM)
    • Brazil
    • Argentina
    • Rest of SCAM

Company Profiles

  • BD
  • B. Braun Medical Inc.
  • ICU MEDICAL INC.
  • EQUASHIELD
  • Corvida Medical
  • Yukon Medical
  • Caragen Ltd
  • Simplivia Healthcare Ltd.
  • JMS CO., LTD
  • Victus, Inc.
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

Closing Mechanism ; Type ; Technology ; Component ; End User , and Geography

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States

Frequently Asked Questions


What is closed system drug transfer device?

The closed system drug transfer devices provides protection against hazardous drugs or vapors during drug preparation and administration. It comprises components which enables filtering of dangerous vapors out of the system. Closed system drug transfer devices plays a major role in protection of healthcare professionals from antineoplastic as well as other harmful medications.

What are the driving factors for the closed system drug transfer devices market across the globe?

The factors that are driving growth of the market are growing adoption of chemotherapies and improvement of regulatory guidelines regarding hazardous drugs.

Who are the major players in the closed system drug transfer devices market?

The closed system drug transfer devices market majorly consists of the players such as BD, B. Braun Medical Inc., ICU MEDICAL INC., EQUASHIELD, Corvida Medical, Yukon Medical, Caragen Ltd., Simplivia Healthcare Ltd., JMS CO., LTD., and Victus, Inc. amongst others.

The List of Companies - Closed System Drug Transfer Devices Market

  1. BD
  2. B. Braun Medical Inc.
  3. ICU MEDICAL INC.
  4. EQUASHIELD
  5. Corvida Medical
  6. Yukon Medical
  7. Caragen Ltd.
  8. Simplivia Healthcare Ltd.
  9. JMS CO., LTD.
  10. Victus, Inc.

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • 3.1 Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • 3.2 Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • 3.3 Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • 3.4 Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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