The vaccine adjuvants market size is projected to reach US$ 7.96 billion by 2031 from US$ 2.79 billion in 2023. The market is expected to register a CAGR of 14.0% during 2023–2031. Technological advancements is likely to remain key trends in the market.

Vaccine Adjuvants Market Analysis

In 2020, NIAID established Vaccine Adjuvant Compendium (VAC) for the collaboration between broader scientific community and NIAID-supported vaccine adjuvant researchers. This network-based tool displays adjuvant characteristics to assist vaccine makers to identify suitable adjuvants for target disease.  Also, support various government authorities to foster vaccine adjuvant R&D, top manufacturers collaborations, and product launches through such business strategies are likely to provide profitable opportunities for the growth of the vaccine adjuvants market during the forecast period.

Vaccine Adjuvants Market Overview

Vaccine Adjuvant Technology encompasses nanotechnology, and its production includes supercritical, critical, or near-critical fluids with or without polar cosolvents such as ethanol [referred to as superfluids (SFS)]. Biodegradable biopolymers are dissolved in SFS and mixed with subunit vaccines in an aqueous solution or as a slurry of nanoparticles. Therefore, such new vaccine adjuvant technologies are being developed to make biodegradable polymer nanospheres (PNS) through novel processes, which allows vaccine manufacturers to rule out the use of organic solvents.

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Vaccine Adjuvants Market: Strategic Insights

Vaccine Adjuvants Market

• 
  CAGR (2023 - 2031)

  14.0%
• Market Size 2023
  US$ 2.79 Billion
• Market Size 2031
  US$ 7.96 Billion

Market Dynamics

GROWTH DRIVERS

• Advantages of Vaccine Adjuvants to Favor Market

FUTURE TRENDS

• Collaborative Efforts for Vaccine Adjuvants

OPPORTUNITIES

• Product Launches and Developments in Adjuvant Studies

Key Players

• SPI Pharma Inc
• GSK Plc
• CSL Ltd
• Seppic SA
• Hawaii Biotech Inc.
• Dynavax Technologies Corp
• InvivoGen SAS
• Croda International Plc
• Novavax Inc
• Phibro Animal Health Corp

Regional Overview

• North America
• Europe
• Asia-Pacific
• South and Central America
• Middle East and Africa

Market Segmentation

Adjuvant Class

• Mineral Salt Adjuvant
• Emulsion Adjuvant
• Liposome Adjuvant

Type

• Human Vaccine Adjuvant
• Veterinary Vaccine Adjuvant

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Vaccine Adjuvants Market Drivers and Opportunities

Advantages of Vaccine Adjuvants to Favor Market

In recent years, adjuvant vaccines have been developed to enhance humoral and cell-mediated immune response after vaccination. By adding adjuvant components, vaccine efficacy is improved. The primary mechanisms of actions of the newer adjuvants involve enhancement of the innate immune system and lead to improved humoral and cell-mediated immunity against infections in populations.

Product Launches and Developments in Adjuvant Studies

Over past decades, non-biogenic adjuvants, biogenic adjuvants, and their multi-type of composite adjuvant materials studies are increasing, aiming at providing a theoretical basis for developing feasible and effective adjuvants for oral vaccines. With increasing studies related to vaccine adjuvants, strategic initiative are also happening in the market. For instance, In August 2023, Bimervax, the COVID-19 vaccine developed by the HIPRA Human Health, received approval from the Medicines and Healthcare Products Regulatory Agency (MHRA). Bimervax is part of the SARS-CoV-2 virus spike protein combined with an adjuvant acting as an additional ingredient designed to trigger a strong immune response. It can also be administered as a booster shot in the upper arm, particularly for those aged 16 years and over. Such approvals for vaccine adjuvants is likely to favor the market growth from 2020 to 2030.

Vaccine Adjuvants Market Report Segmentation Analysis

Key segments that contributed to the derivation of the vaccine adjuvants market analysis are adjuvant class and type.

• Based on adjuvant class, the vaccine adjuvants market is divided into mineral salt adjuvant, emulsion adjuvant, liposome adjuvant, and others. The mineral salt adjuvant segment held a larger market share in 2023.
• By type, the market is bifurcated into human vaccine adjuvant and veterinary vaccine adjuvant. The human vaccine adjuvant segment held the largest share of the market in 2023.

Vaccine Adjuvants Market Share Analysis by Geography

The geographic scope of the Vaccine Adjuvants market report is mainly divided into five regions: North America, Asia Pacific, Europe, Middle East & Africa, and South & Central America.

North America has dominated the market and Asia Pacific is anticipated to grow with the highest CAGR in the coming years. Rising infectious disease and pandemics contribute to accelerating vaccine adjuvant production in Asia Pacific, influencing market growth during 2022-2030. In India, there is high support from the National Institute of Health (NIH), which contributes to the production of vaccines. One such example is the adjuvant developed by NIH funding to enhance the efficacy of India's COVAXIN Alhydroxiquim-II vaccine. The adjuvant used in COVAXIN, named “Alhydroxiquim-II”, was discovered and tested in the laboratory by ViroVax LLC, by incorporating a small molecule attached to “Alhydrogel”, a substance commonly known as alum standing as the most common adjuvant used in the vaccines for people.

Vaccine Adjuvants Market Report Scope

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Vaccine Adjuvants Market News and Recent Developments

The vaccine adjuvants market is evaluated by gathering qualitative and quantitative data post primary and secondary research, which includes important corporate publications, association data, and databases. A few of the developments in the vaccine adjuvants market are listed below:

• SPI Pharma Inc and Q-Vant Biosciences Inc partnered to combines Q-Vant's leadership in sustainable saponin extraction technology with SPI's global reach and servicing expertise in the pharmaceutical industry. This includes investment in expanding Q-Vant’s proprietary 100% sustainable Q-SAP technology and an exclusive commercial agreement to accelerate the global adoption of their saponin adjuvants for veterinary and human vaccine formulations. (Source: SPI Pharma Inc, Press Release, October 2023)
• Seppic launched MONTANIDE GEL P PR, an aqueous adjuvant based on a polymeric technology dedicated to avian injectable vaccines, meeting the need for innocuity in the avian market. In addition, MONTANIDE GEL P PR is particularly stable and can resist destabilising antigenic media frequently used in avian vaccines. (Source: Seppic, Press Release, May 2024)

Vaccine Adjuvants Market Report Coverage and Deliverables

The “Vaccine Adjuvants Market Size and Forecast (2021–2031)” report provides a detailed analysis of the market covering below areas:

• Vaccine adjuvants market size and forecast at global, regional, and country levels for all the key market segments covered under the scope
• Vaccine adjuvants market trends, as well as market dynamics such as drivers, restraints, and key opportunities
• Detailed PEST/Porter’s Five Forces and SWOT analysis
• Vaccine adjuvants market analysis covering key market trends, global and regional framework, major players, regulations, and recent market developments3
• Industry landscape and competition analysis covering market concentration, heat map analysis, prominent players, and recent developments for the Vaccine Adjuvants market
• Detailed company profiles